In the Europa League last-16, West Ham will meet Sevilla, a six-time winner, while Scottish champions Rangers will face Serbia's Red Star Belgrade.
After winning their group, the Premier League side advanced to the last 16. Rangers had to overcome Borussia Dortmund 6-4 on aggregate over two legs in the round of 32 to reach this level for the third year in a row. In the Europa Conference League last-16, Leicester will face Rennes of France.
Both tournaments' first legs will be contested on March 10th, with the second legs on March 17th. Hammers manager David Moyes will go to Spain first, while Rangers will start with a home match at Ibrox.
Sevilla, who won the title for the first time in the 2019-20 season, will host the final at their Ramon Sanchez Pizjuan Stadium. Barcelona has been drawn against Galatasaray of Turkey in the Europa League.
Spartak Moscow will face RB Leipzig of Germany. Because Spartak, the final Russian team remaining in European competition, is unable to play at home due to Russia's invasion of Ukraine, it is unknown where the second leg of that game will be played.
The 2022 Champions League final has also been taken away from Russia.
Last-16 draw for the Europa League:
Crvena Zvezda vs. Rangers
SC AS Monaco vs. Braga
Lyon vs. FC Porto
Bayer Leverkusen vs. Atalanta
West Ham vs. Sevilla
Galatasaray vs. Barcelona
Spartak Moscow vs. RB Leipzig
Eintracht Frankfurt vs. Real Betis
Last 16 of the Europa Conference League
FC Basel against. Marseille
Rennes against Leicester
Gent vs. PAOK
Roma against Vitesse
FC Copenhagen vs. PSV Eindhoven
LASK vs. Slavia Prague
FK AZ vs. Bodo/Glimt Alkmaar
Feyenoord vs. Partizan Belgrade