Townsend fell off right off the bat in the FA Cup rout at Crystal Palace on Sunday and an output uncovered he experienced foremost cruciate tendon harm.
Everton said the 30-year-old "will go through a medical procedure one week from now prior to beginning his restoration".
Townsend's nonappearance comes as Toffees manager Frank Lampard attempts to save his side from Premier League assignment.
Everton are seventeenth in the first class, only two focuses over the last three, in spite of the fact that they truly do have games close by in a portion of the opponent groups around them.
The Goodison Park side are likewise without focus back Yerry Mina due to a quad injury.
The Colombia global was precluded for as long as 10 weeks in the wake of experiencing the injury in an association rout by Newcastle United on 8 February.
Everton's Tom Davies is additionally sidelined in the wake of having a medical procedure on his hamstring, while individual midfielder Allan needs to serve two additional rounds of a three-match suspension.
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