Joe, although a marketer by profession, is a worshiper by calling.^[5] He was born to Florence Addo and Emmanuel Mettle and is the eldest of six children. Joe started his education at the Richard Akwei Memorial School and later moved to Kade 1&2 Primary School (Kade) where he spent about a year before returning to Accra, to the St. Michael's and All Angels. He continued to Korle Gonno 3 Junior High School (JHS) and obtained his Senior High School Certificate from the His Majesty Academy. Joe Mettle is an alumnus of Accra Academy.^[6] Prior to His Majesty Academy, he studied draftsmanship at the Modern School of Draftsmanship (MODESCO). He then attended the Pentecost University College, a private Christian university college located at Sowutuom in Accra.^[6]

During his early days of singing, he worked as a backing vocalist for some Ghanaian Gospel greats including Cindy Thompson, the late Danny Nettey, and Reverend Tom Bright Davies. Joe Mettle was the lead singer for the indigenous multicultural music group, Soul Winners.^[7] He won the Artiste of the Year, Gospel Artiste of the Year and the Male Vocalist Artiste of the Year at the 2017 Vodafone Ghana Music Awards (VGMA). His award for Artiste of the Year was considered historical as he was the first Gospel artiste to win in this category since the conception of these awards.^[8] Joe has also won over 10 local and international awards. He has won several awards at Africa Gospel Music Awards, Gospel industry Awards, African Gospel Awards (UK), CCML Ghana Gospel Awards, Bass Awards and RIGA Awards (South Africa).

Joe has featured on the popular South African Broadcasting Corporation's TV show titled, "Gospel Classics"^[9] which also highlighted Donnie McClurkin. He received the Best Male Gospel Artiste in Africa at the Trumpet Gospel Awards held in South Africa.

He has many nationwide hit songs including "Mehia wo Yesu" (meaning-I need you Jesus), "Nhyira" (meaning-Blessing), "Med? Wo", "Akokyem Nyame", "Mensuro" (meaning-I will not fear), "Turning Around" and "Yesu Adi Nkunim" (meaning-Christ is Victorious) to his credit. One of the songs attributed to him, that won him nominations at the 2017 VGMA is titled "?nwanwani" (meaning-God of Wonders). He has six albums to his credit.^[10]